Some biological properties of Fe(III) complexes

Abstract

The biological properties of some coordination compounds of Fe(III) with organic ligands from different classes of chemical compounds: FeCl3 Digsemi 2H2O (Digsem - dihydrazide of semicarbazidediacetic acid) (I); Fe(N3)LSO4 (L-sulfadiazine) (II); [FeL1(H2O)2](NO3)3•H2O (L1 - condensation product of 2,6-diacetilpyridine with nicotinic acid hydrazide) (III), [FeL2(H2O)2](NO3)3•H2O (L2 - condensation product of 2,6-diacetilpyridine with isonicotinic acid hydrazide) (IV), were studied. The structure of the compounds III and IV was determined by X-ray diffraction method and represents a pentagonal bipyramid, in which L1 and L2 act as neutral pentadentate ligands that coordinate to the iron atoms with the electron donor atom set N3O2, and two water molecules in the apical positions. The iron atoms are heptacoordinated. NO3-anions are located in the external coordination sphere and equilibrate the charge of the metal atoms.