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2023
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Browsing 2023 by Author

Browsing 2023 by Author "CUROCICHIN, Ghenadie"

Now showing items 1-5 of 5

The Implementation of Personalized Medicine in the Republic of Moldova: Challenges and Opportunities in Cardiology

LEVITCHI, Alexei; GALEA-ABDUSA, Daniela; SONTEA, Victor; CUROCICHIN, Ghenadie (Springer Nature Switzerland, 2023)

Implementing Personalized Medicine in the operational and functional context of a healthcare system is a complex challenge for most countries. Pharmacogenetics represents the application domain of individual genetic profile ...
Influence of CYP2C19*2 Polymorphism on Clinical Outcomes in Moldova’s Patients Treated with Clopidogrel After Percutaneous Coronary Intervention

DOGOT, Marta; GALEA-ABDUSA, Daniela; BUZA, Anastasia; GRIB, Andrei; CUROCICHIN, Ghenadie; VATAMAN, Eleonora; CAPROS, Natalia (Springer Nature Switzerland, 2023)

This study evaluated the effect of genetic polymorphism in CYP2C19*2 on clinical response in Moldova’s patients treated with clopidogrel after percutaneous coronary intervention (PCI) with drug-eluting stent (DES). A total ...
Personalised Medicine Implementation in Lowand Middle-Income Countries

GUSILA, Ilenuta; TOPA, Alexandra; ZARBAILOV, Natalia; LUNGU, Natalia; CUROCICHIN, Ghenadie (Springer Nature Switzerland, 2023)

The potential of Personalised Medicine makes it attractive to health systems, and personalised approaches are being applied in practice in highly developed countries. However, the implementation of personalised medicine ...
Personalized Medicine Perspectives and Policies in European Nordic Countries

GARABAJIU, Maria; GALEA-ABDUSA, Daniela; TOPA, Alexandra; GUSILA, Ilenuta; CUROCICHIN, Ghenadie (Springer Nature Switzerland, 2023)

The technical revolution has generated large numbers of data in healthcare and biomedical research. Thus, research and innovation became a growing priority to support a change from the one-size-fits-all paradigm of healthcare ...
The Prevalence of Allele Frequencies of CYP2C19 Polymorphisms of Clinically Important Drug-Metabolizing Enzymes CYP2C19 in Moldova Healthy Population

DOGOT, Marta; GALEA-ABDUSA, Daniela; BUZA, Anastasia; CUROCICHIN, Ghenadie; CAPROS, Natalia (Springer Nature Switzerland, 2023)

Genetic polymorphisms of drug-metabolizing enzymes, such as cytochrome P450 oxidases, can alter the pharmacokinetic properties of administered drugs, leading to variability in drug responses. Prior knowledge of allele ...

Browsing 2023 by Author "CUROCICHIN, Ghenadie"

Browsing 2023 by Author "CUROCICHIN, Ghenadie"

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