Biotechnological Tools in Genetics for Primary Prophylaxis of Essential Arterial Hypertension

Abstract

Hypertension is one of the most spread cardiological diseases, due to recent biotechnological tools it is discovered that arterial hypertension is a polygenic disease. Another possible explanation might be the variety of the studied populations. The current results of genetic analyses of essential hypertension highlight the need for a more differentiated approach to the understanding of complex, polygenetic traits that implements gene-gene- and gene-environment interactions or differentiated functional testing of thoroughly phenotyped cohorts under standardised environmental conditions. The advancement of molecular genetics now permits the establishment of a connection between high blood pressure and certain traits. The aim of this work is to analyse how genetic testing for primary prophylaxis of arterial hypertension can be applied.